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Fig. 1. Increasing synteny detection. Dots on these Oxford grids denote homologous sequences plotted by their genomic locations on duplications (Dup.) 1 and 2. Diagonals are observed between regions having a colinear arrangement of homologous sequences and define synteny. (A) Direct comparison between the diverged duplications reveal a weak diagonal composed of only four data points. (B) Comparisons between Dup. 1 and 2 with a reference that simulates a common ancestor, revealing stronger diagonals with eight and 10 data points, respectively. Dup. 1 and 2 are defined as related by both regions being syntenic to the same portion of the reference.