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Selective Phenotyping to Accurately Map Quantitative Trait Loci

Dep. of Agronomy, Iowa State Univ., 1208 Agronomy Hall, Ames, IA 50011-1010

View larger version (16K): [in a new window]   Fig. 1. Average number of recombinants per cM in 10- and 20-cM marker intervals (lines with symbols, left scale), and total number of recombinants over all selected genotypes (lines without symbols, right scale) as affected by the selected fraction of genotypes. Continuous lines are for the uniRec method and dotted lines are for the maxRec method of selection. Closed symbols are for 20-cM marker spacings and open symbols are for the 10-cM spacing. A selected fraction of 1 indicates no selection. Average number of recombinants for 10- and 20-cM intervals calculated using three chromosomes for each spacing.

View larger version (12K): [in a new window]   Fig. 2. Standard deviation across repeated simulations of the total number of recombinants per centimorgan among the selected genotypes in 10- and 20-cM marker intervals, as affected by the selected fraction of genotypes. Lines and symbols are as for Fig. 1.

View larger version (14K): [in a new window]   Fig. 3. Average QTL position MSE as affected by marker spacing. Closed symbols are for no selection (selected fraction of 1) and open symbols are for a selected fraction of 1/16 under the uniRec method. Whiskers give the 95% confidence interval for the average. Figure 3A is for QTL explaining 11.6% of the phenotypic variance; Fig. 3B is for QTL explaining 5% of the phenotypic variance.