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Bioinformatics Unit, Institut für Pflanzenbau und Grünland, Universität Hohenheim, 70599 Stuttgart, Germany
* Corresponding author (piepho{at}uni-hohenheim.de)
Crop cultivar registration requires multienvironment trials for assessing the value for cultivation and use (VCU). The series of trials usually extends across 3 yr, with some cultivars being discarded each year. Selection gives rise to a missing-data or drop-out pattern that is not completely random. The present paper studies the effect of drop-out on the validity of mixed model procedures such as REML and BLUP. It is shown on the basis of the pertinent statistical theory and simulations that selection is ignorable providing that all data used in the selection process are included in the analysis. Simulations show that REML is preferable to ML and BLUP is preferable to BLUE. It is suggested that cultivar registration authorities can benefit from multivariate mixed model analyses comprising all traits on which selection is based.
Abbreviations: BLUE, best linear unbiased estimation BLUP, best linear unbiased prediction MAR, missing at random MCAR, missing completely at random ML, maximum likelihood MNAR, missing not at random MSE, mean squared error REML, restricted (residual) maximum likelihood VCU, value for cultivation and use
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